Shlimazlnitseh = a bad housekeeper, the female embodiment of domestic clumsiness and ill luck.
Acording to that adorable yidmaven Michael Wex:
It isn't that the shlimazlnitseh can’t be bothered, it's just that she can’t get it together to look after things the way she would like to. This aspect of helplessness helps to distinguish the shlimazlnitseh from the dreaded shlumperkeh, also known as the shtinkerkeh, who is as close as Yiddish comes to an idea of Jewish trailer-park trash, although it often means little more than a neighbor whom your mother dislikes.
Dishes piled high in the sink, mould sprouting from the unwashed floor, the shlumperkeh is a working-class Emma Bovary, in love with her own leavings. Everything is too much for her, housework is beneath her; the shlumperkeh hot ken mol nisht ken koyekh -- she never has the strength or the energy to do what she's supposed to -- despite the fact that not having anything else to do is an essential pre-condition of true shlumperkism: "I have to take the kids to soccer, don't expect me to clean the house!"
The shlimazlnitseh is incompetent;
the shlumperke just doesn’t care.